However, a higher than expected dropout rate indicated that more studies of valaciclovir in patients with HIV are required. Acute graft rejection was also reduced in the valaciclovir-treated group. A small study in heart transplant patients compared valaciclovir 2 g 4 times daily with aciclovir mg 4 times daily and found a significant reduction in CMV antigenaemia favouring valacilovir at the end of the treatment period.
However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1- Use this drug as ordered by your doctor.
Read all information given to you. Follow all instructions closely. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications.
This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. For more resources, visit www. It is used to treat herpes infections. It is used to treat shingles. It is used to treat cold sores. It is used to treat chickenpox. It may be given to you for other reasons. Talk with the doctor.
If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
This drug may interact with other drugs or health problems. What are some things I need to know or do while I take this drug? In short, valacyclovir stops the herpes virus from spreading to healthy cells, reducing the effects of the virus. However, it does make the effects of herpes less severe, meaning the sores developed from the virus heal faster and the aches, cold symptoms and other signs of herpes can become less severe. If you have herpes, valacyclovir reduces the risk of you transmitting the virus to other people.
The amount of time required for valacyclovir to control a herpes or chickenpox outbreak varies based on the severity of the outbreak and how soon you take valacyclovir after noticing herpes symptoms. For most initial herpes outbreaks and cases of recurring herpes, valacyclovir takes effect very quickly and provides some level of relief in as little as two to three days.
Generally, the sooner you take valacyclovir after noticing symptoms, the faster it will be to provide relief. Valacyclovir is available as a generic medication or under several brand names.
In the United States, valacyclovir is most commonly sold as Valtrex, which is the original trade name for the drug marketed by GlaxoSmithKline. Today, valacyclovir is available as a generic medication, meaning there are numerous different trade names in use. Most of the companies manufacturing valacyclovir offer it in several doses, including mg and 1,mg tablets. Generally, the most common dosages are as follows:.
Abstract A screening program for antiviral drugs begun at Burroughs Wellcome in the s resulted in the discovery of acyclovir in Publication types Historical Article. Substances Acyclovir.
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